Please note that thermalign is deprecated and the newer program FractTerm should be used. Click here to use FractTerm
ThermAlign is a program to determine the melting temperature of two
DNA sequences using a nearest-neighbor model.
The version used here requires two DNA-sequences as input. The program can be used with DNA-RNA and RNA-RNA duplexes if the respective thermodynamic parameters are provided. Unpaired bases (bulges) in the duplexes will be considered by the software.
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Diploma Thesis (PS GZIP)
Paper (preliminary version) (PS GZIP)